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15 Best Marijuana Strains for Migraines

by in Medical Marijuana November 8, 2023

The throbbing pain of migraines is not something you can ever get used to. Headaches can start at any time and last for hours or even days. Finding relief can seem impossible, especially for those who don’t want to rely on medications.

Fortunately, there is hope. It comes in the shape of a natural supplement we all know and love. Marijuana! But with so many strains and effects, identifying the right choice can get overwhelming. 

So, we’ve compiled a list of the 15 best marijuana strains for migraines. If you’re exploring natural therapies for your headaches, keep reading to meet some of the most effective solutions. 

Understanding Migraines

Migraines are the third most prevalent disease in the world, affecting over a billion people. They start as severe throbbing pain or pulsing sensations at the side of the head and can sometimes last for days. 

Other symptoms of migraines that the best marijuana strains for headaches may address include:

  • Fatigue
  • Nausea
  • Vomiting 
  • Stiff neck
  • Mood changes
  • Sensitivity to light and sound

Migraine attacks can be triggered by various factors, such as dehydration, lack of sleep, and menstruation. Some patients looking for the best cannabis strains for migraines may even experience warning signs before the headaches start. 

These episodes, known as aura, include signs like seeing light flashes, feeling tingling on one side of the face, or having trouble speaking. Medications may help reduce these symptoms. However, they also have a never-ending list of side effects.

How Can Medical Marijuana Help with Migraines?

Marijuana possesses hundreds of cannabinoids and terpenes that interact with the body’s endocannabinoid system and exert their medicinal effects. While the exact mechanisms are unknown, scientists assume that medical cannabis reduces headaches by decreasing the sensory experience of pain.

Studies exploring the best strains for migraines are also promising. One study in 2016 examined the effects of marijuana on 121 adults diagnosed with migraines. After using cannabis, the frequency of their headaches decreased from 10 to four per month.

Another study in 2015 reviewed the effectiveness of medical cannabis as a natural treatment for chronic migraines. The results showed that patients had fewer headaches while experiencing better sleep, less anxiety, and enhanced mood. 

While more studies are needed to confirm these effects and find the best strains for headaches, these findings show that marijuana can be a safe and helpful ally in the fight against migraines.

The 15 Best Cannabis Strains for Migraines

Dried cannabis buds

There are different types of cannabis products and strains available for various uses. Here are 15 of the best cultivars you can use to find relief from frustrating migraines. 


ACDC is one of the best low-THC strains for beginners who want to try marijuana for their migraines. This strain has up to 6% THC, 24% CBD, and terpenes such as myrcene, pinene, and beta-caryophyllene.

ACDC is a sativa-dominant cross between Cannatonic and Ruderalis that gives off scents of cherry and lemongrass. You can enjoy ACDC whenever you want to find relief without losing focus.

2. Blue Dream 

One of the best strains for migraines is the dreamy Blue Dream. This strain packs 18% THC, 2% CBD, and beneficial terpenes such as myrcene, alpha-pinene, and caryophyllene.

Blue Dream comes from a lineage of Blueberry Indica and Super Silver Haze. So it’s mostly sativa with fruity hints of berry and citrus. Try this strain in the evening to avoid nighttime headaches. 

3. Canna-Tsu

Another of the best strains for headaches is the indica-leaning Canna-Tsu. This cultivar contains 9% THC, 10% CBD, and aromatic terpenes such as linalool, beta-caryophyllene, and myrcene.

Canna-Tsu is the hybrid of CBD-rich parents, Cannatonic and Sour Tsunami. When you try it, you’ll taste sweet and earthy flavors with hints of citrus. Take it any time of the day to give your headaches a run for their money!

4. Cherry Blossom

The fourth cultivar on our list of the best strains for migraines is the indica-dominant Cherry Blossom. This flavorful strain packs an impressive 28% THC and 0.07% CBD with pinene, myrcene, and limonene terpenes.

Cherry Blossom is the descendant of Cherry Pie and Orange Blossom Trail with sweet cherry aromas. For the ultimate fruity experience, try Cherry Blossom!

5. Chocolope

Chocolope, or D-Line, is a pure sativa and one of the best strains for headaches. It gives you 15%-21% THC, nearly zero CBD, and unique terpenes such as terpinolene, myrcene, and ocimene.

This cross between Chocolate Thai and Cannalope Haze is one of the best daytime strains for migraines. If you want to taste the earthy flavor of cannabis with notes of coffee, go for Chocolope!

6. Critical Mass

Your next choice for battling migraines is Critical Mass. This indica-dominant strain has 20% THC, 5% CBD, and sleep-inducing terpenes like myrcene and caryophyllene.

You can try this lovechild of Afghani and Skunk #1 in the evening to calm your throbbing head. One hit of Critical Mass will fill your lungs with herbal scents of cannabis with citrus undertones. 

7. Harlequin

Dried cannabis flower on a wooden surface

Our search for the best strains for migraines continues with Harlequin, a sativa-dominant favorite with 7% THC, 10% CBD, and promising terpenes like myrcene, alpha-pinene, and beta-caryophyllene.

Harlequin comes from a combination of Gold, Swiss, and Thai sativas. It’s also one of the 20 best marijuana strains for PTSD that reduces your headaches and anxiety levels with sweet, tropical aromas.

8. Northern Lights

Next on our list of the best strains for headaches is the indica-dominant Northern Lights, with up to 21% THC, 0.1% CBD, and a rich terpene profile, including myrcene, caryophyllene, and limonene.

Northern Lights comes from Afghani and Thai varieties with potent painkilling abilities. That is why it’s on our list of the best strains for migraines. Try Northern Lights in the evening for a citrusy night free of headaches!

9. OG Kush

Cultivars for headaches must possess potent pain-relieving properties. That is why OG Kush, one of the best marijuana strains for chronic pain, has made our list! OG Kush gives you 20% THC, 0.5% CBD, and terpenes like myrcene and limonene.

Descending from Chemdawg, Lemon Thai, and Old World Paki Kush, this heavy-hitting strain gives off tangy notes of lemon and pine. Try the indica-dominant OG Kush in the evening to tame your throbbing head. 

10. Orangutan 

Another of the best strains for migraines is the indica-dominant Orangutan. This cleverly named strain contains up to 13% THC, 1% CBD, and terpenes like linalool, limonene, humulene, and carene.

Orangutan is a hybrid of Orange Crush and Citrus Sap with apple flavors. Try Orangutan at night for immediate physical relaxation and pain relief. 

11. Pineapple Kush

Another indica-dominant strain on our list is Pineapple Kush. This fruity cultivar is one of the best cannabis strains for headaches, with 24% THC, 4% CBD, and terpenes, including alpha-pinene, beta-caryophyllene, and limonene.

This strain is a cross between Pineapple and OG Kush, and as the name suggests, it boasts a tropical flavor with pineapple notes. Once you take a hit of Pineapple Kush, your headache will subside within minutes!

12. Purple Kush

Next on our list of the best strains for migraines is Purple Kush, a type of purple weed with 20% THC, 0.1% CBD, linalool, myrcene, and limonene terpenes. 

This indica-leaning strain comes from Hindu Kush and Afghani Purple. It exudes sweet grape and berry aromas, making it perfect for those who want relief while masking the scent of cannabis with fruity flavors. 

13. Remedy

Another indica-dominant cultivar among the best strains for headaches is Remedy. This strain has 1% THC, 14% CBD, and some of marijuana’s top anti-inflammatory terpenes, including myrcene, pinene, and caryophyllene.

Remedy is the hybrid of Cannatonic and Afghan Skunk with earthy aromas. Its low THC content makes it one of the best strains for migraines for those who want to avoid the intoxicating side of cannabis.

14. Sour G

Another popular sativa-dominant cultivar for fighting headaches is Sour G. This strain packs 18% THC, 1% CBD, and terpenes such as myrcene and limonene. 

This cross between Sour Diesel and OG Kush gives off citrus and diesel aromas. You can take it in the morning to reduce your migraines and enjoy a relaxed day. 

15. White Widow

Last on our list of the best strains for migraines is White Widow. This indica-dominant cultivar packs 25% THC, 1% CBD, and a variety of terpenes, including myrcene, caryophyllene, and pinene.

This descendant of a Brazilian Sativa and a South Indian Indica has woody, earthy aromas. It’s also one of the strongest marijuana strains available. So try White Widow if you want relief with a sense of euphoria!

Try the Best Marijuana Strains for Headaches with Ozark MMJ Cards

Are you excited to try marijuana for your migraines? Now, you can do so legally with the help of Ozark MMJ Cards!

We offer fast and affordable telehealth medical marijuana card certification and renewal services. Eligible patients in Arkansas, Missouri, and Oklahoma can schedule a meeting with one of our doctors online and get certified. 

Contact us now to begin your certification process and try the best strains for migraines. If you enjoyed this article, don’t forget to check out our cannabis blog for more fun reads!

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